RESEARCH NEWS
FROM HHMI

Mutant Mouse Mimics Human Bone Cancer
(06.16.08)
HHMI researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer.

New Genetic Barcoding Technique Identifies Dozens of Targets for Cancer Drugs
(02.01.08)
HHMI investigators are beginning to examine every gene in the genome to figure out which genes are deleterious to tumor cells.

A Genetic "Gang of Four" Drives Spread of Breast Cancer
(04.12.07)
Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs.

Common Molecule Notifies Immune System of Prostate Cancer
(01.11.08)
In experiments with mice, researchers have found that the body’s immune system can use a surprisingly common molecule to recognize prostate tumors.

HHMI SCIENTISTS AND ANGIOGENESIS

D. Gary Gilliland

Todd R. Golub

Joan Massagué

Shahin Rafii

Boris O. Kopnin

FROM THE HHMI BULLETIN

Putting the Brakes on Cancer
(May 2007)
By reactivating p53—a renowned tumor-suppressor gene—researchers are stopping even advanced cancers in mice.

Bringing Down Cancer's House of Cards
(February 2008)
Defining an elaborate yet fragile control pathway offers a new strategy for toppling many cancers.

FROM BIOINTERACTIVE

Angiogenesis

The Evolution of Cancer

Understanding Cancer Diversity

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HHMI Bulletin: November 2008

Cover Story: The Meiosis Dance
Researchers are finally learning the molecular steps of a chromosome shuffle that's been watched from afar for centuries.

Lab Lessons
If hands-on is the way to teach science, hands-on in a real scientist's lab has got to be the ultimate, right? More programs think so, and they are finding ways to make it happen for high school students.

Carving Out Her Niche
Judith Kimble's engaged style has made for a vibrant career unraveling mechanisms that control stem-cell development—and some interesting airplane chats.

Science 2.0: You Say You Want a Revolution?
The collaborative online tools people are using in other parts of their lives, such as Facebook, YouTube, and blogs, are roiling the disciplined world of scientific communication.