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Researchers Discover Key Gene for Making Motor Neurons
July 25, 2008
Researchers have revealed an important step in the process that guides the early development of neurons as they establish precise connections between the spinal cord and muscles. More
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Eye Movement Disorder Caused by Improper Development of Motor Neurons
July 24, 2008
An international team of researchers has identified a gene mutated in Duane syndrome, a common disorder that restricts the movement of the eyes. More
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Fruit Fly Study Yields a Gene Required for Peaceful Slumber
July 17, 2008
Thanks to a set of fruit flies that seem to get by with far less dozing than most, researchers has found a gene absolutely necessary for snoozing. More
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Middle Eastern Families Help Scientists Pinpoint Autism Genes
July 11, 2008
By focusing on large families in which both parents share a recent ancestor, scientists have honed in on rare mutations that had remained elusive in previous studies. More
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The Mighty MitoCarta—Online Mitochondrial Atlas Leads to Cause of Inherited Disease
July 10, 2008
HHMI-supported scientists have created MitoCarta, an online atlas of more than 1,000 proteins that healthy mitochondria use to keep cells running smoothly—a tool that should help researchers understand what happens when things go wrong.
Its creators have used the resource to identify a genetic mutation responsible for complex I deficiency, a rare, lethal metabolic disorder in infants. More
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Research Identifies Malaria Proteins that Remodel Red Blood Cells
July 09, 2008
After a malaria parasite invades a red blood cell, it sends a crew of proteins inside that gut the cell, transforming it from a vital oxygen delivery system into a nest for new parasites. HHMI international scholar Alan Cowman and his colleagues set out to understand the proteins that oversee this destruction and rebuilding. More
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Fruit Fly Gene Study Could Yield New Flu Treatments
July 09, 2008
Scientists may be able to stave off influenza infection by targeting one of more than 100 proteins inside host cells on which the virus depends. These potential drug targets are the result of a study in which researchers tested the ability of a modified influenza virus to infect fruit fly cells. More
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How the Snake Got Its Vertebrae
June 18, 2008
Researchers have uncovered the mechanism that guides vertebral development in the early embryo and makes sure each species ends up with the right number of vertebrae. More
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Mutant Mouse Mimics Human Bone Cancer
June 16, 2008
HHMI researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer. More
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You've Gotta Have HAART
June 15, 2008
A new model reveals that three classes of HIV drugs inhibit the virus more than 10,000 times better than others. More
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